ACS Fall 2020 Virtual Meeting

August 17-20, 2020

Addressing Chemical Complexity with Nonlinear Optical Microscopy

A symposium in the Physical Chemistry division

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Symposium Description

Despite its introduction over four decades ago, the ability to couple the measurement of nonlinear phenomena with the spatial resolution of a microscope objective has continued to rapidly evolve through both the application of more sophisticated techniques and the study of more complex systems. Progress in the field of nonlinear microscopy has afforded deep penetration in biological tissues, additional modalities for chemical contrast, and dynamics on ultrafast timescales. Challenges remain, however, in extracting new information from increasingly congested samples with minimal perturbation. Innovations in instrumentation, the development of new image analysis methodologies, and novel applications of existing techniques promise new insight into intrinsically heterogeneous samples. This symposium will gather scientists from the fields of chemistry, physics, engineering and biology into a collaborative environment where ideas of technology innovations and sample applications can be shared and discussed. Progress, existing challenges, and impact will be emphasized. Organizers: Tessa Calhoun and Martin Fischer

Important Information:

All presentations will be following by a live Q&A session. Times are shown in Eastern Daylight Savings Time but click the links to automatically add individual presentations to your calendar which should adjust for your time zone. All presentations will be available on Zoom and free for all participants. You can register for free access using the following link: https://duke.zoom.us/meeting/register/tJAkde-uqTIjH9PLIe2aB30PJl2QW1H4IRpR

While this symposium originated as part of the ACS Fall 2020 Virtual Conference, participation in these Zoom sessions is not limited to those registered for the conference. As such, feel free to share this website and its information with any of your colleagues and students that may be interested!
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Monday, August 17

Computational and Developmental Techniques

Presider: Ken Knappenberger
Name Title Start Time (EDT)
Tessa Calhoun and
Martin Fischer
Opening Remarks 8:55 AM
Godofredo Bautista Vector-field nonlinear optical microscopy of nano-objects 9:00 AM
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Joanna Atkin Tailoring near-field interactions for high spatial resolution characterization of materials 9:35 AM
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Arnaldo Serrano Towards Super-Resolution 2DIR Imaging: Wide-Field IR Imaging and Time-Domain Spectroscopy Through Dielectric Microspheres 10:10 AM
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Ji-Xin Chen Optical Photothermal Infrared Microscopy 10:30 AM
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Steve Baldelli Chemical Imaging of Surfaces with Sum Frequency Generation Vibrational Spectroscopy 11:05 AM
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Kieran Farrell Design of a 100 kHz 2D IR spectrometer and 2D IR imaging of pancreata 11:40 AM
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Multimodal Imaging

Presider: Jesse Wilson
Name Title Start Time (EDT)
Bryce Manifold U-within-U-net: a versatile deep learning architecture for analysis of hyperspectral images 1:00 PM
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Kenneth Knappenberger Dissecting the Structure-Optical Interplay in 2D Heterostructures Using Correlative Second Harmonic Imaging and Electron Microscopy 1:20 PM
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Marcos Dantus Spectral and temporal encoding for chemical identification of depth-resolved multimodal nonlinear optical imaging of intact retina 1:55 PM
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Martin Zanni A new instrument for ultrafast transient absorption and 2D white-light microscopy with applications to next generation photovoltaics 2:30 PM
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Renske van der Veen Dynamic Environmental Transmission Electron Microscopy for the Study of (Ultra)Fast Phenomena in Nanoscale Materials 2:50 PM
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Rohit Prasankumar Using Ultrafast Optical Microscopy to Shed New Light on Nanoscale Semiconductors 3:25 PM
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Paul Campagnola Multiscale SHG microscopy analysis of collagen alterations in human diseases 4:00 PM
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Tuesday, August 18

Pump-Probe Imaging

Presider: Erik Grumstrup
Name Title Start Time (EDT)
Fu-Jen Kao Synchronized subharmonic modulation in stimulated emission microscopy 9:00 AM
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John Papanikolas Visualization of Charge Motion in Nanostructures with Pump-Probe Microscopy 9:35 AM
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Gregory Hartland Strong and weak vibrational coupling in metal nanostructures studied by ultrafast microscopy 10:10 AM
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Martin Fischer Visualization of pigment degradation in cultural heritage with transient absorption microscopy 10:30 AM
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Jesse Wilson Modeling transient absorption response of hemeproteins for redox-sensitive mitochondrial imaging contrast 11:05 AM
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Jason Malizia Spatially Resolving the Ultrafast Dynamics of Thin MoS2 Nanoflakes with Pump-Probe Microscopy 11:40 AM
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Megan Steves Spatially-resolved two-dimensional electronic spectroscopy for probing the dynamics of heterogeneous systems 12:00 PM
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Materials for Energy Applications

Presider: Joanna Atkin
Name Title Start Time (EDT)
Libai Huang Ultrafast Dynamic Microscopy of Exciton and Charge Transport 1:00 PM
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Elham Ghadiri Ultrafast Spectroscopy and Microscopy of Nanostructured Solar Cells 1:20 PM
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Kathryn Knowles Photophysics and Electronic Structure of Solution-Processed Nanostructured Thin Films of Hematite 1:55 PM
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Max Verkamp Transient absorption microscopy of singlet fission and charge carrier injection in PDI-silicon heterojunctions 2:30 PM
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Erik Grumstrup Direct Correlation of Charge Carrier Transport to Local Crystal Quality in Lead Halide Perovskites 2:50 PM
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Renee Frontiera Probing singlet fission and exciton transport with femtosecond stimulated Raman spectro-microscopy 3:25 PM
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Wednesday, August 19

Applications in Biology I

Presider: Luke Mortensen
Name Title Start Time (EDT)
Tong Ye Assessing the Chondrocyte Viability in Articular Cartilage with Intrinsic Nonlinear Optical Signatures 9:00 AM
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Yingzhong Ma Co-registered multimodal all-optical imaging in spatially heterogeneous systems 9:35 AM
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Brandon Colon Total Internal Reflection Transient Absorption Microscopy: An Online Detection Method for Microfluidics 10:10 AM
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Norbert Scherer Snapshot Multifocal Microscopy and Nanoscale 3D Tracking of Insulin Granule Dynamics in Beta Cells 10:30 AM
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Mikhail Drobizhev Two-photon polarization ratio Ω is sensitive to a local protein – fluorescent probe interaction 11:05 AM
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Ahmed Heikal Effects of tumor-like 3D culture on the metabolic activities of murine breast cancer cells using two-photon fluorescence lifetime imaging microscopy of intrinsic NAD(P)H 11:25 AM
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Ian McFarlane Dual near-infrared exciton-emission two photon microscopy for 3D imaging of biological systems 11:45 AM
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Raman Imaging

Presider: Tong Ye
Name Title Start Time (EDT)
Kevin Welsher Uncovering solvation heterogeneity in live cells via hyperspectral stimulated Raman scattering microscopy 1:00 PM
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Francisco Robles Stimulated Raman scattering spectroscopic optical coherence tomography 1:20 PM
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Conor Evans Pharmacokinetic Tomography: Imaging Drug Uptake with Chemical Microscopy 1:55 PM
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Lixue Shi Super-multiplexed vibrational imaging for three-dimensional proteomic phenotyping 2:30 PM
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Lu Wei Stimulated Raman Imaging for Complex Bioanalysis 2:50 PM
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Dan Fu A multimodal nonlinear optical microscopy platform for in vivo mouse brain imaging 3:25 PM
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Thursday, August 20

Applications in Biology II

Presider: Francisco Robles
Name Title Start Time (EDT)
Garth Simpson Unfogging the Tensor: Divining Molecular Organization from Polarization-Dependent Nonlinear Optical Imaging through Turbid Media 9:00 AM
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Kimani Toussaint Quantitative Second-Harmonic Generation Microscopy for Assessment of Collagenous Tissues 9:35 AM
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Yang Li Simultaneous two- and three-photon excitation fluorescence of NADH 10:10 AM
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Luke Mortensen Nonlinear microscopy for the evaluation of bone health and regeneration 10:30 AM
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Uvinduni Premadasa Spatially Co-Registered Nonlinear Optical Imaging of Complex Biological Systems in a Total Internal Reflection Geometry 11:05 AM
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Seong Kim Sum Frequency Generation Spectroscopy Study of Mesoscale Polar Order of Cellulose Microfibrils at Cellular Level in Intact Plant Cell Walls 11:25 AM
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