Addressing Chemical Complexity with Nonlinear Optical Microscopy
A symposium in the Physical Chemistry division
Symposium Description
Despite its introduction over four decades ago, the ability to couple the measurement of nonlinear phenomena with the spatial resolution of a microscope objective has continued to rapidly evolve through both the application of more sophisticated techniques and the study of more complex systems. Progress in the field of nonlinear microscopy has afforded deep penetration in biological tissues, additional modalities for chemical contrast, and dynamics on ultrafast timescales. Challenges remain, however, in extracting new information from increasingly congested samples with minimal perturbation. Innovations in instrumentation, the development of new image analysis methodologies, and novel applications of existing techniques promise new insight into intrinsically heterogeneous samples. This symposium will gather scientists from the fields of chemistry, physics, engineering and biology into a collaborative environment where ideas of technology innovations and sample applications can be shared and discussed. Progress, existing challenges, and impact will be emphasized. Organizers: Tessa Calhoun and Martin Fischer
Important Information:
All presentations will be following by a live Q&A session.
While this symposium originated as part of the ACS Fall 2020 Virtual Conference, participation in these Zoom sessions is not limited to those registered for the conference. As such, feel free to share this website and its information with any of your colleagues and students that may be interested!Computational and Developmental Techniques
Presider: Ken Knappenberger
| Name | Title |
|---|---|
| Tessa Calhoun and Martin Fischer | Opening Remarks |
| Godofredo Bautista | Vector-field nonlinear optical microscopy of nano-objects |
| Joanna Atkin | Tailoring near-field interactions for high spatial resolution characterization of materials |
| Arnaldo Serrano | Towards Super-Resolution 2DIR Imaging: Wide-Field IR Imaging and Time-Domain Spectroscopy Through Dielectric Microspheres |
| Ji-Xin Chen | Optical Photothermal Infrared Microscopy |
| Steve Baldelli | Chemical Imaging of Surfaces with Sum Frequency Generation Vibrational Spectroscopy |
| Kieran Farrell | Design of a 100 kHz 2D IR spectrometer and 2D IR imaging of pancreata |
Multimodal Imaging
Presider: Jesse Wilson
| Name | Title |
|---|---|
| Bryce Manifold | U-within-U-net: a versatile deep learning architecture for analysis of hyperspectral images |
| Kenneth Knappenberger | Dissecting the Structure-Optical Interplay in 2D Heterostructures Using Correlative Second Harmonic Imaging and Electron Microscopy |
| Marcos Dantus | Spectral and temporal encoding for chemical identification of depth-resolved multimodal nonlinear optical imaging of intact retina |
| Zach Armstrong | A new instrument for ultrafast transient absorption and 2D white-light microscopy with applications to next generation photovoltaics |
| Renske van der Veen | Dynamic Environmental Transmission Electron Microscopy for the Study of (Ultra)Fast Phenomena in Nanoscale Materials |
| Rohit Prasankumar | Using Ultrafast Optical Microscopy to Shed New Light on Nanoscale Semiconductors |
| Paul Campagnola | Multiscale SHG microscopy analysis of collagen alterations in human diseases |
Pump-Probe Imaging
Presider: Erik Grumstrup
Materials for Energy Applications
Presider: Joanna Atkin
Applications in Biology I
Presider: Luke Mortensen
| Name | Title |
|---|---|
| Tong Ye | Assessing the Chondrocyte Viability in Articular Cartilage with Intrinsic Nonlinear Optical Signatures |
| Yingzhong Ma | Co-registered multimodal all-optical imaging in spatially heterogeneous systems |
| Brandon Colon | Total Internal Reflection Transient Absorption Microscopy: An Online Detection Method for Microfluidics |
| Norbert Scherer | Snapshot Multifocal Microscopy and Nanoscale 3D Tracking of Insulin Granule Dynamics in Beta Cells |
| Mikhail Drobizhev | Two-photon polarization ratio Ω is sensitive to a local protein – fluorescent probe interaction |
| Ahmed Heikal | Effects of tumor-like 3D culture on the metabolic activities of murine breast cancer cells using two-photon fluorescence lifetime imaging microscopy of intrinsic NAD(P)H |
| Ian McFarlane | Dual near-infrared exciton-emission two photon microscopy for 3D imaging of biological systems |